PPT Slide

Applications (I)

• Gene Discovery
  • TIGR gene was cloned in 1997 as the first and the most important glaucoma gene discovered
  • At least one novel glaucoma gene has been identified and cloned, verification is in progress
  • A few other glaucoma genes are mapped

• Gene Expression
  • A regulatory protein of the TIGR gene was identified
  • A reporter gene system has been set up to screen for small molecules modulating TIGR gene expression

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