Cost
Basis
Unrealized
Other-Than-
Temporary
Impairment
Loss
Estimated
Fair Value
December 31, 2014
Gains
Losses
Equity securities:
Regulus Therapeutics Inc. . . . . . . . . . . . . . . . . . . . . . . . . . $ 12,477 $69,404 $ — $ — $ 81,881
Total equity securities . . . . . . . . . . . . . . . . . . . . . . . . . . $ 12,477 $69,404 $ — $ — $ 81,881
Total available-for-sale and equity securities . . . . . . . . . . . . $619,366 $69,576 $(1,154) $ — $687,788
Amortized
Cost
Unrealized
Other-Than-
Temporary
Impairment
Loss
Estimated
Fair Value
December 31, 2013
Gains Losses
Available-for-sale securities:
Corporate debt securities(1) . . . . . . . . . . . . . . . . . . . . . . .
$142,096 $ 75 $ (27)
$ — $142,144
Debt securities issued by U.S. government
agencies(1). . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
23,242 22 (16)
— 23,248
Debt securities issued by the U.S. Treasury. . . . . . . . . . .
6,239
6
— — 6,245
Debt securities issued by states of the United States
and political subdivisions of the states. . . . . . . . . . . . .
8,082
6 (28)
— 8,060
Total securities with a maturity of one year or less . .
179,659 109 (71)
— 179,697
Corporate debt securities. . . . . . . . . . . . . . . . . . . . . . . . . .
265,969 177 (393)
— 265,753
Debt securities issued by U.S. government agencies. . . .
41,308
3 (127)
— 41,184
Debt securities issued by the U.S. Treasury. . . . . . . . . . .
9,062 21
— — 9,083
Debt securities issued by states of the United States
and political subdivisions of the states. . . . . . . . . . . . .
14,186 37 (28)
— 14,195
Total securities with a maturity of more than one
year. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
330,525 238 (548)
— 330,215
Total available-for-sale securities . . . . . . . . . . . . . . .
$510,184 $347 $(619)
$ — $509,912
Cost
Basis
Unrealized
Other-Than-
Temporary
Impairment
Loss
Estimated
Fair Value
December 31, 2013
Gains
Losses
Equity securities:
Regulus Therapeutics Inc. . . . . . . . . . . . . . . . . . . . . . . . . . $ 15,526 $36,570 $ — $ — $ 52,096
Securities included in other current assets . . . . . . . . . . . .
1,538
618 — (880)
1,276
Securities included deposits and other assets. . . . . . . . . .
625
— — — 625
Total equity securities . . . . . . . . . . . . . . . . . . . . . . . . . . $ 17,689 $37,188 $ — $(880)
$ 53,997
Total available-for-sale and equity securities . . . . . . . . . . . . $527,873 $37,535 $(619)
$(880)
$563,909
(1) Includes investments classified as cash equivalents on our consolidated balance sheet.
F-22
