Isis Pharmaceuticals, Inc. Form 10K - page 165

For the years ended December 31, 2014, 2013 and 2012, we used the following weighted-average
assumptions in our Black-Scholes calculations:
Employee Stock Options:
December 31,
2014
2013
2012
Risk-free interest rate. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
1.7% 1.1% 1.1%
Dividend yield . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
0.0% 0.0% 0.0%
Volatility . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
50.1% 51.1% 50.7%
Expected life. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4.7 years 5.1 years 5.1 years
Board of Director Stock Options:
December 31,
2014
2013
2012
Risk-free interest rate. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
2.2% 2.2% 1.3%
Dividend yield . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
0.0% 0.0% 0.0%
Volatility . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
54.2% 52.7% 51.3%
Expected life. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6.9 years 7.2 years 7.6 years
ESPP:
December 31,
2014
2013
2012
Risk-free interest rate. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
0.1% 0.1% 0.1%
Dividend yield . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
0.0% 0.0% 0.0%
Volatility . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
60.1% 62.9% 44.5%
Expected life. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 months 6 months 6 months
Risk-Free Interest Rate.
We base the risk-free interest rate assumption on observed interest rates appropriate
for the term of our stock option plans or ESPP.
Dividend Yield.
We base the dividend yield assumption on our history and expectation of dividend payouts.
We have not paid dividends in the past and do not expect to in the future.
Volatility.
We use an average of the historical stock price volatility of our stock for the Black-Scholes
model. We computed the historical stock volatility based on the expected term of the awards.
Expected Life.
The expected term of stock options we have granted represents the period of time that we
expect them to be outstanding. We estimated the expected term of options we have granted based on actual and
projected exercise patterns.
Forfeitures.
We reduce stock-based compensation expense for estimated forfeitures. We estimate forfeitures
at the time of grant and revise, if necessary, in subsequent periods if actual forfeitures differ from those
estimates. We estimate forfeitures based on historical experience. Our historical forfeiture estimates have not
been materially different from our actual forfeitures.
6. Income Taxes
We have net deferred tax assets relating primarily to net operating loss carryforwards, or NOL’s, and
research and development tax credit carryforwards. Subject to certain limitations, we may use these deferred tax
assets to offset taxable income in future periods. Since we have a history of losses and the likelihood of future
profitability is not assured, we have provided a full valuation allowance for the deferred tax assets in our balance
sheet as of December 31, 2014. If we determine that we are able to realize a portion or all of these deferred tax
assets in the future, we will record an adjustment to increase their recorded value and a corresponding adjustment
to increase income or additional paid in capital, as appropriate, in that same period.
Intraperiod tax allocation rules require us to allocate our provision for income taxes between continuing
operations and other categories of earnings, such as other comprehensive income. In periods in which we have a
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