Heparin vs. LMWH vs. Arixtra
PROTECT designed to show a 30 day fixed dose oral heparin regimen is superior to a ten day injected fixed dose Lovenox regimen
- With no less than equivalent safety
- Neither product requires monitoring
Injected Arixtra comparable safety and efficacy to injected Lovenox.
- LABEL; “Differences in efficacy and safety between ARIXTRA and enoxaparin may have been influenced by factors such as timing of the first dose after surgery.”
- Dose adjustment required based on patient’s age
- Monitoring required for patients with renal disease
Oral Heparin: Competition