2002 Program Initiatives/Milestones

• Oral LMW Heparin: Phase I data

• Oral UFH Heparin (solid): Enter Phase I/II

• Oral Insulin: Initiate long term tox studies; initiate Type I dosing studies; initiate multiple dose patient studies

• Oral Insulin: Partnership discussions continued

• Oral PTH: Phase I data

• Oral rhGH: Initiate Phase I testing in Q3’02

• Oral Cromolyn: patient data in allergy patients

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