PPT Slide
Alfimeprase Phase II: Catheter Occlusion
Indication: Catheter occlusion
Design: Multi-center, randomized, double-blind study
Comparison of three doses of alfimeprase against the approved dose of Cathflo®Activase® (alteplase) to restore function in occluded central venous catheters in ~100 patients in 20 centers in the U.S.
Lead investigator, Dr. Steven Deitcher of the Cleveland Clinic
Timeline: Dosing commenced June 3, 2003
Endpoints: Safety Restoration of flow Time to lysis