SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

Form 10-K

  ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d)
OF THE SECURITIES EXCHANGE ACT OF 1934
  For the fiscal year ended October 31, 2001
or
  TRANSITION REPORT PURSUANT TO SECTION 13 OR15(d)
OF THE SECURITIES EXCHANGE ACT OF 1934
  For the transition period from           to           .

Commission File Number 001-15167
BIOPURE CORPORATION
(Exact name of Registrant as specified in its charter)

Delaware
(State or other jurisdiction of
incorporation or organization)
11 Hurley Street, Cambridge, MA
(Address of principal executive offices)		   04-2836871
(I.R.S. Employer
Identification No.)
02141
(Zip Code)

Registrant’s telephone number, including
(617) 234-6500

Securities registered pursuant to Section 12(b) of the Act:
NONE

Securities registered pursuant to Section 12(g) of the Act:
Common Stock, $0.01 par value per share
Preferred Stock Purchase Rights
(Title of Class)

      Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days.     Yes           No 

      Indicate by check mark if disclosure of delinquent filers pursuant to Item 405 of Regulation S-K is not contained herein, and will not be contained, to the best of registrant’s knowledge, in definitive proxy or information statements incorporated by reference in Part III of this Form 10-K or any amendment to this Form 10-K.     

      Based on the closing price on January 16, 2002, and assumptions relating to the privately held non-voting Class B Common Stock, the aggregate market value of the voting and non-voting common equity held by nonaffiliates of the registrant was $346,122,600.

      The number of shares outstanding of the registrant’s Class A Common Stock was 25,711,346 on January 16, 2002; the number of shares of the Class B Common Stock was 117.7.

Documents Incorporated By Reference

Location in Form 10-K      Incorporated Document
Part I   Specifically identified portions of the registrant’s definitive proxy statement to be filed in connection with the registrant’s Annual Meeting to be held on April 3, 2002.