Item 6. Selected Financial Data

     Set forth below is selected financial data for the five years ended October 31, 2001.

Fiscal Year Ended October 31,
In thousands, except per share data 2001 2000 1999 1998 1997
Statements of Operations Data:
Total revenues   $     3,489     $     3,063     $     2,866     $     1,131     $      
Cost of revenues     3,665       4,778       6,814       1,543        
Gross profit (loss)     (176 )     (1,715 )     (3,948 )     (412 )      
Operating expenses:
  Research and development     34,609       26,378       24,166       22,950       23,494  
  Sales and marketing     2,807       2,463       2,922       2,444       694  
  General and administrative     15,365       9,878       5,266       4,660       2,920  
Total operating expenses     52,781       38,719       32,354       30,054       27,108  
Loss from operations     (52,957 )     (40,434 )     (36,302 )     (30,466 )     (27,108 )
Total other income, net     3,538       4,356       772       419       (310 )
Net loss     (49,419 )     (36,078 )     (35,530 )     (30,047 )     (27,418 )
Stock dividends on preferred stock                 (17,915 )            
Net loss applicable to common stockholders   $     (49,419 )   $     (36,078 )   $     (53,445 )   $     (30,047 )   $     (27,418 )
Basic net loss per common share   $     (1.97 )   $     (1.51 )   $     (3.61 )   $     (2.41 )   $     (2.23 )
Weighted-average common shares
    outstanding
    25,066       23,947       14,813       12,460       12,300  
Pro forma basic net loss per common share                   $     (2.62 )   $     (1.65 )        
Pro forma weighted-average common shares
    outstanding
                    20,369       18,237          

At October 31,
In thousands 2001 2000 1999 1998 1997
Balance Sheet Data:
Cash and cash equivalents   $     36,089     $     88,828     $     30,778     $     6,063     $     13,527  
Total current assets     42,249       95,920       38,277       13,175       15,221  
Working capital     35,952       84,928       27,872       1,986       5,368  
Net property and equipment     30,162       25,061       27,447       29,606       27,408  
Total assets     84,187       121,287       66,230       44,848       44,054  
Long-term debt (including current portion)     5,205                   6,000       8,000  
Common stock to be repurchased                       6,300       6,300  
Total stockholders’ equity     70,893       108,510       54,037       21,449       20,222  

     The following is a summary of quarterly (unaudited) financial results:

                                                                     
4Q ’01 3Q ’01 2Q ’01 1Q ’01 4Q ’00 3Q ’00 2Q ’00 1Q ’00
In thousands, except per share data
Statements of
    Operations Data:
Total revenues   $   970     $   946     $   838     $   735     $   920     $   836     $   710     $   598  
Gross profit (loss)     (108 )     43       (76 )     (35 )     (352 )     (379 )     (392 )     (591 )
Operating expenses:
  Research and
    development
    7,123       10,297       9,002       8,187       3,747       6,229       8,143       8,259  
  Sales and marketing     737       784       664       622       698       617       569       579  
  General and
    administration
    2,001       1,538       8,753       3,073       3,501       1,529       1,736       3,112  
    Total operating
    expenses
    9,861       12,619       18,419       11,882       7,946       8,375       10,448       11,950  
Loss from operations     (9,969 )     (12,576 )     (18,495 )     (11,917 )     (8,298 )     (8,754 )     (10,840 )     (12,541 )
Other income, net     578       654       990       1,316       1,502       1,563       933       358  
Net loss   $   (9,391 )   $   (11,922 )   $   (17,505 )   $   (10,601 )   $   (6,796 )   $   (7,191 )   $   (9,907 )   $   (12,183 )
Per share data:
  Basic net loss per
    common share
  $   (0.37 )   $   (0.47 )   $   (0.70 )   $   (0.42 )   $   (0.27 )   $   (0.29 )   $   (0.42 )   $   (0.55 )
  Weighted-average shares
    used in computing
    basic net loss per
    common share
    25,208       25,134       24,958       24,960       24,937       24,933       23,580       22,282  

     In the third quarter of fiscal 2001, research and development expenses include a one-time expense of $1,604,000, of which $1,511,000 is non-cash, for intellectual property and pre-clinical studies related to the acquisition of Reperfusion Systems, Inc., an inactive company 26% owned by Biopure prior to the acquisition.

     General and administrative expenses include non-cash compensation expense for stock options and warrants granted to certain consultants and directors. This non-cash compensation must be accounted for at fair value, per SFAS 123 and EITF 96-18, and be amortized over the vesting period and revalued each quarter based on the closing stock price. The quarterly expenses/ (credits) to operations for fiscal 2001 were ($80,000), ($793,000), $6,370,000 and $1,347,000 for the fourth, third, second and first quarters, respectively. The quarterly expenses/ (credits) to operations for fiscal 2000 were $1,895,000, ($34,000), $131,000 and $1,688,000 for the fourth, third, second and first quarters, respectively.