Pursuant to the requirements of Section 13 or 15(d) of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

Dated: January 29, 2002 BIOPURE CORPORATION



  By:  /s/ FRANCIS H. MURPHY
    Francis H. Murphy
    Chief Financial Officer

     Pursuant to the requirements of the Securities Exchange Act of 1934, this Annual Report has been signed below by the following persons on behalf of the Registrant and in the capacities and on the dates indicated.

             
Signature Title Date
 
/s/ CARL W. RAUSCH

Carl W. Rausch
  Chairman and Chief
Executive Officer
  January 29, 2002
 
/s/ DAVID N. JUDELSON

David N. Judelson
  Director, Vice Chairman   January 29, 2002
 
/s/ PAUL A. LOONEY

Paul A. Looney
  Director, President   January 29, 2002
 
/s/ DANIEL P. HARRINGTON

Daniel P. Harrington
  Director   January 29, 2002
 
/s/ C. EVERETT KOOP, M.D.

C. Everett Koop, M.D.
  Director   January 29, 2002
 
/s/ CHARLES A. SANDERS, M.D.

Charles A. Sanders, M.D.
  Director   January 29, 2002
 
/s/ J. RICHARD CROUT, M.D.

J. Richard Crout, M.D.
  Director   January 29, 2002
 
/s/ FRANCIS H. MURPHY

Francis H. Murphy
  Chief Financial Officer   January 29, 2002