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The Pathway HT system targets
the field of high content cell
analysis for the pharmaceutical,
biotechnology, academic and
government research markets.


Biosciences is building upon its leadership in cell analysis with the most extensive line of flow cytometry instrumentation, addressing the broadest range of applications. That position is complemented by in vitro drug candidate toxicity screening products from the Discovery Labware unit and cell signaling reagents from the Pharmingen unit. For scientists engaged in basic research or drug discovery, this combination of competencies makes BD Biosciences a supplier of choice.

    A large part of BD Biosciences' mission is to support biomedical research by providing tools and technology to scientists pursuing promising discoveries. That means the Company must offer leading-edge solutions–customers demand it. There are several key drivers of innovation at BD:
  • Close relationships with leading researchers that stimulate BD Biosciences' own innovation.
  • In-depth experience and technical insight that provide a solid base from which to launch innovation.
  • Well-respected scientists and technologists who are disciplined in addressing the needs of the market.
  • A total systems approach–not only reagents or instruments, but the entire solution.
    In flow cytometry, the BD FACSAria cell sorter was a key factor driving strong sales for BD and growing the size of the flow cytometry market over the 2003-2004 period. The BD FACSAria cell sorter represents a revolutionary advancement in flow cytometry, not only through higher levels of performance, but also through ease of use and convenience as it requires no time-consuming optical alignment or special room modifications.

    The 2004 acquisition of Atto Bioscience offers numerous synergies with the existing BD portfolio. It provides another major instrument platform, in addition to our family of flow cytometers, and expands our position in cell biology. It also complements BD's expertise in drug toxicity testing, which remains a hurdle in the drug discovery process; it links well with Pharmingen's expertise in fluorescent proteins; and it fits well with Discovery Labware's plates for imaging. In turn, BD Biosciences' worldwide reach provides the opportunity for Atto products to be sold well beyond their current U.S. focus. A substantial majority of Atto's business is in the U.S., so it stands to gain from BD's worldwide presence, sales and service. For drug companies involved in the high throughput screening used for drug discovery, the Pathway HT system delivers high content analysis earlier in the process.





BD recently enhanced its cytometric bead array (CBA) line with the launch of a CBA Flex Set that allows investigators to custom configure their assays for greater sensitivity.
Compact and easy to use, the BD FACSAria cell sorter represents the most successful launch of a sorter in the history of the flow cytometry industry.

BD Gentest hepatocytes are liver cells used by pharmaceutical companies to test the safety of developmental drugs. Novel BD Falcon Flip-Lock packaging maintains cell quality during shipping.

Newly developed medicines can make a vast difference in quality of life. Often, patients just want to get back to doing normal, daily tasks. Remarkably, only one among many thousands of screened compounds ultimately receives FDA approval to become a new medicine.

It takes an estimated $800 million or more, and an average of 10 to 15 years, to develop a new drug. The Pathway HT imaging system is designed to provide high resolution images for use in developing cellbased assays, making drug discovery more effective and efficient, and helping to get new drugs to patients faster.

The system became part of BD Biosciences' drug discovery product portfolio as a result of BD's 2004 acquisition of Atto Bioscience. Its ability to investigate living cells in real time holds the potential to accelerate the pace at which new medicines can be developed.



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