TO OUR
SHAREHOLDERS,
EMPLOYEES AND
CUSTOMERS:
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C. William Zadel Chairman, President and Chief Executive Officer
  Francis J. Lunger Executive Vice President, Chief Operating Officer    
 
     Year 2000 started with a reorganized management team and high expectations for continued growth in Millipore’s revenue and profitability. These expectations were met and then exceeded. The microelectronics industry entered one of its hypergrowth stages this year reaching a new peak in August, 2000, and we were ready with an expanded product line and the manufacturing flexibility to match demand. We also saw continuing growth in biotechnology-derived pharmaceuticals and had the technology breadth and applications expertise to help biotech companies bring these to market. There were also some very exciting developments in life science research that created new growth opportunities for Millipore, and we acted on these opportunities with new alliances and new platforms of products.
    Revenues for 2000 were $954 million, an increase of 24 percent compared to 1999 revenues, and, in local currency, an increase of 26 percent. Earnings for the year were $2.48 per diluted share compared with $1.35 per diluted share in 1999 when non-recurring items were excluded.
   The microelectronics industry growth cycle accelerated to full speed during 2000. Millipore’s microelectronics business followed this trend and grew to record levels of revenue and profitability. We supported our customers in meeting their high demand and advancing new manufacturing processes including copper deposition and chemical mechanical planarization. Revenue for the year in microelectronics grew 71 percent in dollars and 70 percent in local currency. Operating income for the year grew 304 percent versus 1999 in local currency, highlighting the profitability leverage that comes with revenue growth in this business.
    Millipore’s bioscience business was favorably impacted by two growth engines — biotech drug manufacturing and life science research. Biotechnology-derived drugs continue to grow as a percentage of the total pharmaceutical market and Millipore’s extensive product line of filtration, purification and chromatography products continue to add value in manufacturing these therapeutics. Life science research, particularly in areas of genomics, proteomics and drug development, also grew significantly during 2000. This research, taking place in government and academic laboratories as well as in the labs of pharmaceutical and genomics companies, utilizes Millipore’s large and growing line of products for sample preparation, purification and capture. Of particular note: we completed customer testing of new genomics sample preparation kits in 2000, the first of which was introduced worldwide this January. Late in 2000, we also formed an alliance with Applied Biosystems to create the next generation of sample preparation devices for proteomics.
   Revenues for Millipore’s bioscience business grew 10 percent in 2000 versus 1999 in local currency and 6 percent in dollars. Operating income for the year grew 18 percent versus 1999 in local currency, again highlighting the profitability leverage Millipore gains with revenue volume growth.
    During 2000, as our two businesses experienced strong growth, the differences between the businesses became increasingly obvious. This observation was not new information, but it became more important because the magnitude of the difference had increased with the growth of each business.

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