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David Durack, M.D., Vice President–Corporate Medical Affairs, sums up the Company's HIV/AIDS efforts when he says, "We are involved in the battle against HIV/AIDS at every level, from high-tech monitoring systems to reuse prevention syringes for developing countries that cost just pennies each." His perspective highlights the fact that BD possesses broad-based expertise that enables it to make contributions across the continuum of HIV/AIDS care. BD works to: prevent the spread of the disease through needle reuse prevention and improved healthcare worker safety; diagnose infections, such as tuberculosis, which is the number one infectious killer of people with HIV/AIDS; monitor the efficacy of antiretroviral treatments with high-quality CD4 counts; provide tools that enable research of the disease, and support those who seek to develop a vaccine against it.

The establishment of a coordinated HIV/AIDS strategy two years ago leverages capabilities resident in each of BD's three worldwide business segments, making BD's ongoing efforts more effective and uncovering additional opportunities for the Company to contribute. "Coordinating our strategy has enabled us to articulate all that we can do and, seeing this, BD associates are very pleased that the Company has made such a major commitment," says Krista Thompson, Vice President and General Manager, HIV/AIDS.

BD also works toward better relationships with governments, nongovernmental organizations and nonprofits–and with positive results. Since 1996, for example, BD has collaborated with the Brazilian government to create a monitoring protocol for HIVpositive patients. When the program started, the average life expectancy for an infected patient was 14 months. Today, with regular CD4 testing and the proper drug therapy, the 180,000 patients in the program are experiencing dramatically improved life expectancies.

Relationships lead to progress
BD's long-term relationship with Dr. Robert Rennie, whose work is highlighted here, enables a leading microbiologist (a former president of the Canadian Association for Clinical Microbiology and Infectious Diseases with a worldwide reputation) to make inroads in the battle against bacterial infections, particularly healthcare–associated infections (HAI).

BD's leading-edge capabilities in the diagnosis of these infections are also reflected in work with the National Public Health Service for Wales to create a network to detect incidents of HAI and the emergence of microorganisms resistant to antibiotics, with the goal of preventing serious complications in hospitalized patients. John Hanson, President, BD-Europe, says BD set up a system to analyze individual patients' bacterial infections using BD Phoenix systems situated in 12 clinical laboratories across Wales. Then, to enable broad-based monitoring, BD linked the instruments to a BD EpiCenter Microbiology Data Management System. The networked system made Wales, a country of just three million people, the first in Europe to have a nationwide monitoring capability and to serve as a model for other countries, including England, Scotland and Germany, that are investigating their own systems.



 Curing infection




Robert Rennie, Ph.D., one of Canada's senior clinical microbiologists, wanted to equip his laboratory at the University of Alberta Hospital in Edmonton with the most advanced technology for Identification and Antimicrobial Susceptibility Testing (ID/AST). Dr. Rennie compared three competing automated microbiology systems to investigate which system would enable him to provide physicians with the fastest, most reliable diagnoses of patients' bacterial infections and help to direct effective drug therapy. Dr. Rennie concluded that the BD Phoenix Automated Microbiology System offered an opportunity for a new technology that would rapidly identify pathogens and give rapid and accurate identification of the most important antimicrobial resistance markers. Dr. Rennie placed a BD Phoenix system in his laboratory–the first BD Phoenix system to be installed in a North American hospital. Says Dr. Rennie: "I measure ID/AST systems by their ability to accurately identify bacteria causing infections and detect emerging antimicrobial resistance, the time it takes to obtain that information, and then assist in directing optimal antimicrobial treatment. Early institution of appropriate therapy leads to improved patient outcomes."





The BD Phoenix Automated Microbiology System detects bacterial resistance rapidly and assists with optimal patient therapy. The BD Phoenix system can perform up to 200 simultaneous identification and susceptibility tests, and can deliver accurate results in 4-16 hours– rapid for the microbial world. Among its competitive advantages, the BD Phoenix system identifies more than 300 organisms–significantly more than that of the nearest competitor. When certain organisms unique to Canada proved difficult to identify, BD worked with Dr. Rennie to design tests that provided the solution.






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