PPT Slide
Oral insulin was safe and well-tolerated
- no hypoglycemia in diet-controlled subjects
- no SAEs
- no weight gain
OGTT data shows evidence of effect
- clinically relevant decreases in fasting blood glucose, 2 hr post-load glucose, and blood glucose AUC
Oral insulin absorption evident
- clear peaks observed at 15-20 minutes post-dose
- oral insulin efficacy observed in “real-life” outpatient dosing design
Decreased fasting blood glucose
- Significant decreases in mean FBG
Emisphere – Multi-Dose Study Conclusions