Study Summary

In patients with type 2 diabetes:

• Bedtime dosing with oral insulin suppresses overnight-fasting insulin secretion

• Bedtime dosing with oral insulin may improve fasting hepatic insulin sensitivity, evidenced by unchanged fasting glycemia with reduced fasting insulinemia

• The physiologic actions of oral insulin are exerted far longer (ɴ hrs) than predicted by its rapid systemic pharmacokinetics (Cmax @ 25 min)

• Whether long-term treatment with oral insulin may preserve ß-cell function warrants further study

Previous slide

Next slide

Back to first slide

View graphic version