1993  1994  1995  1995  1995  1995  1995  1996  1996 1996 1996 1997 1997 1997 1998
 July  June  March  August  October  November  November  January  March  June  September  February  April  August  January  September  December
 Guilford Pharmaceuticals Inc. 
 Founded
 Guilford completes IPO 
 Guilford completes manufacturing 
 facility for GLIADEL Wafer
 Guilford completes $19.5 million public 
 offering of common stock
 Guilford receives clearance for
 GLIADEL Wafer Treatment IND 
 Guilford signs GLIADEL Wafer
 collaboration with Orion-Farmos 
 Guilford announces GLIADEL Wafer 
 Phase III European trial results
 Guilford announces corporate partnership 
 with Daiichi Radioisotopes Ltd. for
 DOPASCAN Injection
 Guilford completes $46 million public 
 offering of common stock
 Guilford signs worldwide marketing 
 agreement for GLIADEL Wafer
 with Rhône-Poulenc Rorer
 (excludes Scandinavia and Japan)
 Guilford receives FDA marketing 
 clearance for GLIADEL Wafer
 Rhône-Poulenc Rorer launches
 GLIADEL Wafer in the US
 Guilford completes $75 million
 public offering of common stock 
 Amgen enters into agreement with 
 Guilford for Neuroimmunophilin
 Ligand Program
 Multinational Phase III clinical trial 
 of GLIADEL Wafer begins for
 newly diagnosed patients with
 malignant glioma
 Guilford selects lead NAALADase
 inhibitor for clinical development 
 Guilford receives international health 
 authority approvals for GLIADEL
 Wafer in Canada and France