Unique Capabilities in Drug Delivery

All Drug Candidates

> 60% Soluble

< 40% Insoluble

Microprecipitation/ Homogenization

Coating Technologies

NanoEdge Features

and Progress

• Broad applicability

• Small particle size (0.3 to 10 microns)

• High loading density of drugs (10-200 mg/ml)

• Increased dosage and safety

• Multiple delivery options (IV, IM, ID, Oral, Pulmonary)

• Scalable manufacturing demonstrated 5 ml to 600 L)

• Strong IP position (10 patents filed in 2002)

• Long-term stability (2 years at RT)

• Adjustable pharmacokinetics

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