Target Optimization: High Resolution Protein Analysis

Isoelectric Focusing Gel

• Higher level of terminal sialic acid confirmed on BHK vs CHO cell-derived Epo

• Bio-analytical expertise supports production and clinical development of Epo omega

• Platform for analysis of complex biopharmaceuticals

EPO Omega

EPO Alpha (CHO Cell)

EPO Omega (BHK Cell)

Percent TA Completely Sialylated

4

33

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