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THE ISSUE
"With some 40 million people worldwide infected by HIV five million in 2001 alone, according to UNAIDS - there is no greater healthcare priority than developing a preventive AIDS vaccine."
- Kent J. Weinhold, Ph.D., Principal Investigator, National Institutes of Health Central Laboratory, HIV Vaccine Trials Network, and Professor of Surgery and Professor of Immunology, Duke Medical Center




OUR EXPERTISE
BD Biosciences is the worldwide leader in flow cytometry instrumentation and reagents for the clinical management of patients infected with HIV and for research into the development of an AIDS vaccine that could one day eradicate the disease. Drawing on their in-depth understanding of immune function, BD Biosciences scientists are working actively with pharmaceutical and biopharmaceutical companies to assess the efficacy of a new class of AIDS vaccines.


OUR CONTRIBUTION
BD Biosciences offers
a complete portfolio of
instrumentation, software,
monoclonal antibodies and
research reagents for use
by investigators and clinical
laboratories studying cell function and monitoring patients with immune
                 system disorders.
                 The capabilities
                 of the extensive
                 line of BD FACS
                 flow cytometry
                 systems have
                 been continually
                 enhanced, most
                 recently through
                 the introduction of
                 automated systems
for sample preparation and
handling that increase
throughput and improve
the utility of BD FACSCalibur
systems.
BD is waging the war on AIDS on two fronts–
patient monitoring and disease prevention


BD Biosciences’ expertise in flow cytometry has long been an important resource for clinical laboratories helping patients manage their disease. The BD FACSCount instrument used with BD FACSCount CD4 reagents and the BD FACSCalibur system used with BD Multiset reagents are proven platforms for monitoring the immune status of an infected patient.
    BD Biosciences’ leading edge flow cytometry applications also are found in the research environment, where it has introduced the BD multiwell autosampler, allowing researchers to load 96- and 384-well plates onto the high performance BD FACSCalibur system. For scientists seeking to develop an AIDS vaccine, the multiwell autosampler permits greater throughput, reduced sample volume, increased flexibility in experiment design and database-driven software for improved analysis.
    BD Biosciences’ research flow cytometry “tool kits” provide all the components needed for experiments, along with specific protocols for each. Among new research reagents, the BD cytometric bead array is an assay that helps investigators simultaneously measure multiple analytes such as cytokines in serum samples. In addition, the BD FastImmune cytokine system helps validate vaccine efficacy with a focus on measuring white blood cell responses to viruses and other infectious agents. Results can be obtained in just a few hours, compared to days for other methods.
    BD Biosciences’ flow cytometry instruments and reagents are true platform technologies that are finding broad application in the development of therapeutic vaccines to treat immune function diseases, such as autoimmunity, cancer and AIDS.
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