Lessons from Landmark Diabetes Studies:Intervention Works, But at a Price #2

Weight Gain

Diabetes Care 1988;11:567-573

JAMA 1998;280:140-146

Lancet 1998; 352:837-853

DCCT (Type 1)

UKPDS (Type 2)

0

3

6

9

12

15

7.5

5.0

2.5

0.0

Intensified

Conventional

Change in weight (kg)

Years from Randomization

30

25

20

15

10

5

0

-5

1

2

3

4

Quartile of Weight Gain

Mean change in weight (kg)

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