PPT Slide
Ideal Local Delivery Thrombolytic: Alfimeprase
More Rapid Clot Lysis
- Directly fibrinolytic, does not need to convert plasminogen to plasmin
- Expected lysis of clots in 1-4 hrs compared to 24-36 hrs with other thrombolytics
Safer
- Lytic activity confined to delivery site
- Reduced systemic toxicity (intracerebral hemorrhage, systemic bleeds, clotting factor consumption)
Lower Costs/Potential Premium Pricing
- Less time in ICU
- Lower incidence of adverse events