Heart Coronary Arteries and Bypass Grafts Thrombus in the coronary arteries and bypass grafts can cause lack of oxygen (ischemia) in the heart muscle and may cause a damaging heart attack.
Legs: Peripheral Arteries Blood clots can occur in the leg arteries causing debilitating pain. If severe and left untreated, the ischemia may lead to limb amputation.
Dialysis Access Conduits Kidney failure patients rely on surgically-created fistulas or synthetic grafts for regular dialysis. But these can develop blockages requiring clot removal on a regular basis. More than 285,000 de-clotting procedures are performed each year in the U.S.
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