Index Introduction Dear Fellow Shareholders Our Products Product Characteristics Republic of South Africa Approval Accredited Medical Education Program  Physician Q&A Phase III Clinical Trials U.S. Market Opportunity Medical Readiness 2001 Highlights Form 10-K Biopure Corporate Information Shareholder Information

1. Nature of Business and Organization  2. Significant Accounting Policies  3. Transactions with Related Parties  4. Inventories  5. Investment in Affiliate  6. Accrued Expenses  7. Long-Term Debt  8. Deferred Compensation  9. Stockholders’ Equity 10. Employee Benefit Plan 11. Income Taxes 12. Commitments 13. Major Customers 14. Subsequent Events 15. Quarterly Financial Information (Unaudited)