F-6
ISISPHARMACEUTICALS, INC.
CONSOLIDATEDSTATEMENTSOFSTOCKHOLDERS’EQUITY
YearsEndedDecember 31, 2013, 2012and 2011
(In thousands)
IsisPharmaceuticals, Inc. Stockholders’Equity
Common stock
Additional
paid in
Accumulated
other
comprehensive Accumulated
Total
stockholders’
Description
Shares
Amount
capital
income (loss)
deficit
equity
Balance atDecember 31, 2010
...............
99,394 $
99 $1,000,181 $
949 $ (756,687) $ 244,542
Net loss .....................................................
—
—
—
—
(84,801)
(84,801)
Change inunrealized gains (losses),
net of tax ..............................................
—
—
—
(1,719)
—
(1,719)
Issuance of common stock in connection
with employee stockplans ....................
646
1
3,566
—
—
3,567
Warrants exercised ....................................
3
—
—
—
—
—
Share-based compensation expense ..........
—
—
9,845
—
—
9,845
Balance atDecember 31, 2011
...............
100,043 $
100 $1,013,592 $
(770) $ (841,488) $ 171,434
Net loss .....................................................
—
—
—
—
(65,478)
(65,478)
Change inunrealized gains (losses),
net of tax ..............................................
—
—
—
13,250
—
13,250
Issuance of common stock in connection
with employee stockplans ....................
1,438
2
9,468
—
—
9,470
2
5
8
percent convertible subordinated
notes redemption, equity portion ..........
—
—
(12,041)
—
—
(12,041)
2
3
4
percent convertible senior notes,
equity portion, net of issuance costs .....
—
—
57,560
—
—
57,560
Share-based compensation expense ..........
—
—
8,571
—
—
8,571
Balance atDecember 31, 2012
...............
101,481 $
102 $1,077,150 $ 12,480 $ (906,966) $ 182,766
Net loss .....................................................
—
—
—
—
(60,644)
(60,644)
Change inunrealized gains (losses),
net of tax ...............................................
—
—
—
8,600
—
8,600
Issuance of common stock in connection
with employee stockplans ....................
5,372
5
62,953
—
—
62,958
Issuance of public common stock .............
9,618
9
173,283
—
—
173,292
Share-based compensation expense ..........
—
—
11,418
—
—
11,418
Balance atDecember 31, 2013
...............
116,471 $
116 $1,324,804 $ 21,080 $ (967,610) $ 378,390
See accompanyingnotes.