F-5
ISISPHARMACEUTICALS, INC.
CONSOLIDATEDSTATEMENTSOFCOMPREHENSIVELOSS
(In thousands)
YearsEndedDecember 31,
2013
2012
2011
Net loss .................................................................................................... $
(60,644) $
(65,478) $
(84,801)
Unrealizedgains (losses) on investments, net of tax ...............................
10,253
13,250
(1,719)
Reclassification adjustment for realized gains included innet loss .........
(1,653)
—
—
Comprehensive loss ................................................................................. $
(52,044) $
(52,228) $
(86,520)
See accompanyingnotes.
