Edwards Lifesciences 2005 Annual Report"

Shareholder Letter

Financial Gains and New Product Introductions
Our solid financial performance created a strong platform from which we continue to grow. We met or exceeded all of our 2005 financial goals, achieving sales in excess of $998 million and improving our gross profit margin by more than 200 basis points. Non-GAAP net income grew 20%, and we also delivered free cash flow of $126 million. We continued to grow and gain share in our Heart Valve Therapy and Critical Care franchises, while improving these product lines’ profitability. On an underlying basis, all of Edwards’ businesses posted higher sales growth rates over last year, and presently more than 80% of our sales come from products in #1 global market positions.
   Our R&D investment, which we increased nearly 14% this year, is yielding considerable returns, with newer products representing a growing proportion of our sales and further extending Edwards’ leadership in key areas. New product introductions included our PERIMOUNT Magna valve with ThermaFix treatment, Theon mitral tissue valve and Geoform valve repair ring in the U.S., as well as our PERIMOUNT Magna mitral valve in Europe. We also unveiled one of the most exciting new advancements in surgical heart valve treatment — our Ascendra minimal access heart valve system, which enables aortic heart valve replacement to be performed on a patient’s beating heart. We also introduced the FloTrac sensor and Vigileo monitor, the first innovations from a next-generation Critical Care platform that should yield a number of additional, less-invasive technologies in the coming years.

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