Edwards Lifesciences 2005 Annual Report"

Shareholder Letter

Looking Ahead
Edwards will seek to further extend growth and leadership in our chosen areas of emphasis: heart valve disease, critical care technologies and peripheral vascular disease. We will continue emphasizing differentiated, physician-preference products with leadership potential, further building upon the contributions we have been fortunate to make. We also expect to continue investing aggressively in innovative technologies — balancing disciplined growth with new platforms that will enable us to treat even more patients whose conditions are under-diagnosed or untreated.
   For 2006, we are confident in our ability to achieve our financial goals, generating total sales between $1.02 and $1.06 billion (equating to an underlying growth rate of 8-10%); increasing gross profit margin by 150 to 200 basis points; delivering non-GAAP net income growth of 12-15% excluding the impact of special items and stock option expensing, and generating free cash flow of $140 to $150 million.
   Over the decades since Miles Lowell Edwards first started his laboratory, Edwards has pledged to serve as a trusted partner in the community fighting cardiovascular disease. We remain a proud member of the medical technology community, which through its innovations, has contributed to extending patient longevity, increasing productivity and reducing hospitalizations around the world.
   We expect the demand for Edwards’ technologies to continue growing, as more patients require treatment for their advanced cardiovascular conditions, amplified by the increasing aging population and the progressive nature of this disease. While we are proud of our accomplishments to date, helping patients is our life’s work, and there is much yet to do. We thank you for your interest and support as we continue to pursue our aspirations while serving our customers, patients, employees and shareholders.

Sincerely,

Michael A. Mussallem

This letter to shareholders contains figures that are not prepared in
conformity with Generally Accepted Accounting Principles (“GAAP”).
Management has determined that inclusion of these non-GAAP figures
provides a more meaningful comparison of the company’s ongoing
operations. For a reconciliation of GAAP to non-GAAP figures, see the
inside back cover of the accompanying Annual Report and SEC Form 10-K.