Isis Pharmaceuticals, Inc. Form 10K - page 76

76
Ernst&YoungLLP, an independent registeredpublic accounting firm, audited the effectiveness of our internal control over
financial reporting as ofDecember 31, 2013, as stated in their attestation report, which is included elsewhere herein.
Changes in InternalControl overFinancial Reporting
The above assessment did not identify any change inour internal control over financial reporting that occurredduringour
latest fiscal quarter and that hasmaterially affected, or is reasonably likely tomaterially affect, our internal control over financial
reporting.
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