Isis Pharmaceuticals, Inc. Form 10K - page 109

F-21
The following is a summaryof our investments (in thousands):
Other-Than-
Temporary
Amortized
Unrealized
Impairment
Estimated
December 31, 2013
Cost
Gains
Losses
Loss
FairValue
Available-for-sale securities:
Corporate debt securities(1) ................................ $ 142,096 $
75 $
(27) $
— $ 142,144
Debt securities issuedbyU.S. government
agencies (1) .....................................................
23,242
22
(16)
23,248
Debt securities issuedby theU.S. Treasury ........
6,239
6
6,245
Debt securities issuedby states of the
UnitedStates andpolitical subdivisions of
the states ..........................................................
8,082
6
(28)
8,060
Total securitieswith amaturityof one
year or less ..................................................
179,659
109
(71)
179,697
Corporate debt securities .....................................
265,969
177
(393)
265,753
Debt securities issuedbyU.S. government
agencies ...........................................................
41,308
3
(127)
41,184
Debt securities issuedby theU.S. Treasury ........
9,062
21
9,083
Debt securities issuedby states of the
UnitedStates andpolitical subdivisions of
the states ..........................................................
14,186
37
(28)
14,195
Total securitieswith amaturityofmore
thanone year ...............................................
330,525
238
(548)
330,215
Total available-for-sale securities ............... $ 510,184 $
347 $
(619) $
— $ 509,912
Other-Than-
Temporary
Cost
Unrealized
Impairment
Estimated
December 31, 2013
Basis
Gains
Losses
Loss
FairValue
Equity securities:
Regulus Therapeutics Inc. ....................................... $ 15,526 $ 36,570 $
— $
— $ 52,096
Securities included inother current assets ..............
1,538
618
(880)
1,276
Securities included indeposits andother assets ......
625
625
Total equity securities ......................................... $ 17,689 $ 37,188 $
— $
(880) $ 53,997
Total available-for-sale and equity securities ............. $ 527,873 $ 37,535 $
(619) $
(880) $ 563,909
I...,99,100,101,102,103,104,105,106,107,108 110,111,112,113,114,115,116,117,118,119,...134
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